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Celiac disease and gluten sensitivity are often confused because both can cause symptoms after eating gluten. However, they are fundamentally different conditions with different causes, risks, and long-term effects.
Celiac disease is an autoimmune disorder. When someone with celiac disease consumes gluten, their immune system attacks the small intestine, leading to inflammation and damage to the intestinal lining.
Over time, this can result in nutrient deficiencies and serious health complications if not properly managed.
Non-celiac gluten sensitivity does not involve an autoimmune response or intestinal damage. However, it can still cause uncomfortable symptoms such as:
Unlike celiac disease, it does not cause long-term intestinal injury.
Because symptoms overlap, proper testing is essential before removing gluten from the diet. A misdiagnosis can lead to unnecessary dietary restrictions or missed medical conditions.
A gastroenterologist can help determine whether symptoms are due to celiac disease, gluten sensitivity, or another digestive issue.
Understanding the difference between celiac disease and gluten sensitivity is important for proper treatment and long-term digestive health.
Disclaimer: This blog is for informational purposes only and not a substitute for professional medical advice. Consult your healthcare provider for guidance tailored to your health needs.
Krishna Rayapudi, MD, DABOM Board-Certified Gastroenterologist

Learn more about Dr. Rayapudi here: gastrooffice.com/provider/krishna-rayapudi-md-dabom
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